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The resulting inflammatory environment contributes to synaptic loss and cognitive decline

Targeting the acidic tumor microenvironment: unexpected pro-neoplastic effects of oral naHCO3 therapy in murine breast tissue

Strong preclinical coverage: improved insulin sensitivity in aged and high-fat-fed mice (Lee et al., Cell Metabolism 2015) and roughly doubled treadmill running time in old mice (Reynolds et al., Nature Communications 2021)

Additionally, an increase in the CD4+/CD8+ ratio among FM + NCWS patients after a gluten-free diet was observed, as well as a reduction in IL-17 and IL-22 levels

Loss of GPx1 induces ER stress (Geraghty et al., 2016

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