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If it cannot be produced by the body, it is necessary to obtain the B-12 our bodies needs through the food we eat and/or dietary supplements

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Reusable pens (with replaceable cartridges) may have higher initial costs but lower long-term costs for high-volume settings like clinics

B12 absorption occurs primarily in the terminal ileum via intrinsic factor-mediated uptake, with approximately 1% absorbed through passive diffusion at high doses

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