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Supplementary Figure 7 Dose-dependent effects of vitamin D supplementation A common intervention for our participants was vitamin D supplementation

Supplementation with gamma-glutamylcysteine has shown to increase cellular glutathione levels above homeostasis [14] and therefore proves to have potential value as a preventative therapy for osteoporosis by reducing oxidative stress and optimizing Vitamin D and calcium absorption

DECLARATIONS Acknowledgements We are grateful for the valuable discussions and computational resources provided by the Beijing Computational Science Research Center (CSRC), and acknowledge the support from the Talent Hub for AI+ New Materials Basic Research

As we further understand pathophysiological nuances, pharmacological approaches may provide improved symptom control

& Sippl, M

Calcium oxalate is one of the primary forms of kidney stones with uric acid stones being more rare3