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Specifically, NEDD4, a crucial E3 ubiquitin ligase, reduces its binding affinity with Caspase-11 and subsequent Caspase-11 ubiquitination in bone marrow-derived macrophages (BMDMs) through lactylation at K33

Exosomal MicroRNA-181a derived from mesenchymal stem cells improves gut microbiota composition, barrier function, and inflammatory status in an experimental colitis model

To integrate human scRNA-seq data (Cui et al, 2024) with our mouse data (see Fig

In this study we characterized the expression of various ferroptosis markers that include those involved in iron accumulation, iron release, deficient glutathione metabolism, and increased lipid peroxidation at different times after spinal cord contusion injury in mice

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

We emphasize that the use of NAMPT inhibitors in combination with disulfiram, as demonstrated in this study, should be restricted to OV cases with confirmed NAMPT dependence