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Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans

This oxidative damage exacerbates the demyelination process and contributes to neuronal injury (127)

doi: 10.1016/j.arr.2022.101619 99

Broad phenotypic changes associated with gain of radiation resistance in HNSCC

The GSH binding site is conserved and is occupied in several virus structures The patch of positive charge within the I site is conserved across a panel of enteroviruses (note strict conservation in VP1 of R216 and R229 and the presence of either K or R at 233 in Fig

In breast cancer and colorectal cancer, there are similar findings that exosomes adds to the immunosuppressive metastatic microenvironment and facilitates tumor cell spreading [308]