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Indoleamine 2,3 dioxygenase and metabolic control of immune responses

Although they are a part of the normal human gastrointestinal and vaginal flora, they may act as opportunistic human pathogens [157]

Groups of Syrian golden hamsters (36/sex per dose) were exposed for 52 weeks (7 h/day, 5 days/week) to a concentration gradually reduced from 4500 mg/m 3 in week 9 to 2970 mg/m 3 in week 52

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For example, aged animals exhibited reduced expression of the 2-AG synthesising enzyme DAGL [47], but increased expression of the AEA synthesising enzyme N -acyl phosphatidyl ethanolamide-phospholipase D (NAPE-PLD) compared to younger mice [52]

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