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These wide-ranging effects explain why glutathione depletion has been associated with accelerated aging, increased disease susceptibility, impaired detoxification capacity, and compromised immune responses

The mucous membranes appeared slightly tacky, consistent with an estimated dehydration level of 35%

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It can also enhance Vitamin C absorption and improve lymphocyte activity

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Additionally, a decreased response to oral methionine has been observed in men older than 45 years (Silberberg et al, 1997)