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Study on chemical constituents differences between armeniacae amarum semen and Persicae semen based on high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry

Statistical analysis between groups was performed using MannWhitney and KruskalWallis tests

Research has demonstrated that sirtuin activity decreases proportionally with NAD+ depletion, with studies showing 50-70% reductions in sirtuin activity when cellular NAD+ levels decline by 30-40%

Structured from the figure, the GSH and other peptide and protein is different, it's a special peptide bond in the molecule,by glutamate gamma carboxyl (-COOH) and alpha amino-cysteine (NH2) peptidebond condensation

The two-hit vascular hypothesis of Alzheimer's disease proposes that BBB dysfunction allows neurotoxins to enter the brain parenchyma, which in turn leads to neuroinflammation[43]