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This increases the risk that: Products may be contaminated or mislabeled Adverse events may not be monitored or reported Patients may be misled about efficacy 4

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A number of studies have shown that holotranscobalamin (the complex between transcobalamin II and vitamin B12) may be more reliable indicator of the status of vitamin B12 [14]

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Available animal studies suggest relatively short circulating persistence for the parent compounds, although reported values vary substantially depending on study design , analytical method, and peptide formulation