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10.1523/JNEUROSCI.4341-06.2007 [DOI] [PMC free article] [PubMed] [Google Scholar] Raichle, M

We observed a decrease in glutathione synthesis in both cell lines

In particular, CD38 is the main NAD-degrading enzyme in several mammalian tissues [6,19, 34-40]

Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine