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The prevalence of the 677 T mutated allele (patients having at least one 677 T mutated allele) reaches 87%

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However, challenges remain and the field is working toward addressing these unmet needs

Di Blasi, A

Fawn Dorr, Kenduskeag

The cytosolic Grx1-roGFP2 and to a lesser extent the plastidic TKTP-Grx1-roGFP2 lines exhibited lower fluorescence intensity when excited at 488 nm after 24 h or 48 h of AITC treatment compared to their respective control, indicating oxidative conditions and/or lower levels of glutathione (Fig