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In agreement with in vitro findings, DMF treatment induced the expression of Cbs, Ahcy, and NRF2 targets such as Gclc, Gclm, and Slc7a11, but not that of Cse (Fig

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This pH-dependent behavior provides a mechanism for increasing the bioavailability of niclosamide in simple solutions for more direct application to the mucin-covered epithelia as nasal and throat sprays

The comfort benefit is marginal and not worth the additional room temperature exposure