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Box plots present five sample statistics: minimum, lower quartile, median, upper quartile, and maximum

market, there have been efforts to restrict or regulate them

28 note to investors, William Blair analysts wrote that Applied Therapeutics suspects the CRL was related to the efficacy package as opposed to [chemistry, manufacturing and controls] or safety. Results from the Phase III ACTION-Galactosemia Kids study, unveiled in April 2023, showed that govorestat fell short of its primary efficacy endpoint, a composite of four clinical measures designed to assess various domains of galactosemia symptoms

This research was supported by US Department of Energy (DOE) grant DE-FC09-93R18262, DOE Environmental Science Management Program grant DE-FG07-96ER20257 and NIH grant RO1 GM52216

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