glutathione sulfur deficiency Frontiers Impact of Sulfur Deficiency and

Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface

Plant Physiol 133:748760 Navrot N, Collin V, Gualberto J, Gelhaye E, Hirasawa M, Rey P, Knaff DB, Issakidis E, Jacquot J-P, Rouhier N (2006) Plant glutathione peroxidases are functional peroxiredoxins distributed in several subcellular compartments and regulated during biotic and abiotic stresses

doi: 10.1038/s41583-021-00535-8, 88 LiB.SuutariB

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Discussion In a recent study 31 , we have shown that PDI plays an important role in mediating erastin-induced ferroptosis in HT22 cells through catalyzing the conversion of NOS monomer to its homodimer, which subsequently leads to accumulation of NO, ROS and lipid-ROS, and ultimately ferroptotic cell death