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Prevalence of adenylosuccinate lyase deficiency based on aggregated exome data

NAR also activates signaling pathways such as PI3K/Akt and Nrf2/ARE, which are known to regulate cellular defense responses and promote survival under stress conditions (27)

[DOI] [PMC free article] [PubMed] [Google Scholar] 181.Long M.W., Gortmaker S.L., Ward Z.J., Resch S.C., Moodie M.L., Sacks G., et al

The food intake also decreased in the tumor-bearing mice (Fig