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186 This action triggers MGMT degradation, making it a suicide protein

KI3, Taixi

Patients with B-12 deficiency along with a history of excessive alcohol intake and poor dietary intake may have underlying malabsorption conditions

In addition, another NCI-MATCH trial study further confirmed Capivasertib achieved an ORR of approximately 20% in patients with AKT E17 mutations, further validating its therapeutic value for AKT mutant tumors (231)