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When the number of Bacteroides is low, the amount of hydrogen produced by Bacteroides is also reduced, thus weakening the brains defenses against hydrogen, which is thought to be the cause of dementia ( Figure 4 )

It accounts for less than 1% of COPD cases but results in onset of COPD at an earlier age (20-50 years)

The use of calpain inhibitors in hippocampal ischemic neurons was found to reduce the severity of injury (Manev et al., 1990, 2010), but the use of calpain inhibitors did not yield any toxic or protective effect (Manev et al., 2010)

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