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The idea behind this is that the two proteins target different steps of the regeneration process, one being migration and mobilization of the cytoskeleton, and the other one being vascularization and cytoprotection

This condition is known as GH deficiency (GHD) but in analogy with other pituitary deficiencies leading to peripheral hormone deficiencies the term secondary IGF-I deficiency was proposed (Rosenfeld et al)

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Expression levels of GS and GR were elevated in all treatment groups (200-800 M UA) as compared to the non-treated group

The degradation ratio (%) was calculated as fol- lows (2): in which Wd is the initial dry weight, and Wt is the dry weight at a given time point

18 In a micromass chondrogenesis model with human bone marrow-derived MSC (BMSC) cells, BMP peptide was demonstrated to increase the production of glycosaminoglycan (GAG)