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Description

10.1016/bs.vh.2022.01.001 209 ScarmeasN.SternY.MayeuxR.LuchsingerJ

Pracinostat combined with azacitidine in newly diagnosed adult acute myeloid leukemia (AML) patients unfit for standard induction chemotherapy: PRIMULA phase III study

Common dosage: between 500 mg and 2,000 mg per day as needed

What the MTHFR

The most comprehensive evidence comes from three sources: the Phase 2 trial published in the New England Journal of Medicine , the Phase 3 TRIUMPH-4 trial, and a systematic review and meta-analysis that synthesized data from 878 total participants across three randomized controlled trials