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A diverse range of host DNA repair mechanisms, including base and nucleotide excision, Fanconi anemia pathway, HR, and NHEJ, play crucial roles in HIV-1 integration and post-integrational DNA repair 151,152,153,154,155,156

USA 101 , 46374642 (2004)

5 This is significant because the proteins encoded by these genes facilitate the autophagic clearance of dysfunctional mitochondria, a quality control mechanism called mitophagy

Moreover, all the animals habituated to the open-field boxes on three consecutive days prior to the testing, therefore minimizing the effects of novelty as a potential confounding factor

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This approach includes inhibiting transporters and key metabolic enzymes to reduce nutrient uptake and utilization, as well as decreasing the production and release of metabolites such as lactate to remodel the TME