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Progranulin suppressed autoimmune uveitis and autoimmune neuroinflammation by inhibiting th1/th17 cells and promoting treg cells and M2 macrophages

In the paper, they analyzed data from the Etiology of Pneumonia in the Community (EPIC) Study, a prospective active surveillance study of 1,735 adults admitted to the hospital with clinical and radiographic evidence of pneumonia

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Typically, organic florescent dyes are used due to their commercial availability, high quantum yield and the availability of documented protocol to encapsulate them into PLGA nanocarriers 6

Pathological studies have shown that iNOS-expressing macrophages can be detected in AAV lesions, suggesting that the metabolic reprogramming of arginine toward the NO pathway is closely associated with the activation of pro-inflammatory macrophages (102)