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CD28 stimulation activates the PI3K-Akt pathway, leading to enhanced aerobic glycolysis mediated by downstream pathways [105]

found that -HB could inhibit the apoptosis of dopaminergic cells that were exposed to MPTP in relation to the upregulation of Bcl-2/Bax mRNA

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1 H-NMR (400 MHz, CDCl 3 ) ppm = 7.94 (dd, J = 1.2 Hz, J = 3.7 Hz, 1H, Ar-H), 7.73 (dd, J = 0.6 Hz, J = 8.2 Hz, 1H, Ar-H), 7.62 (dd, J = 0.6 Hz, J = 1.5 Hz, 1H, Ar-H), 7.59 (dd, J = 1.2 Hz, J = 5.0 Hz, 1H, Ar-H), 7.39 (dd, J = 1.5 Hz, J = 8.2 Hz, 1H, Ar-H), 7.21 (dd, J = 3.7 Hz, J = 5.0 Hz, 1H, Ar-H), 3.72 (bs, 2 H, -CH 2 -), 3.40 (bs, 2 H, -CH 2 -), 1.751.66 (m, 4 H,-CH 2 -(x2)), 1.641.55 (m, 2 H, -CH 2 -)

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