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The first freeze-thaw cycle causes 3050% potency loss through mechanical denaturation, and a second cycle compounds the damage to the point where the solution has negligible bioactivity

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Light, oxygen, and reactive residues Certain residues are more prone to oxidation or photochemical change

Studies have examined gastric mucosal lesion repair, ulcer models, colitis models, and various inflammatory bowel disease analogues (PMID 17186181, PMID 38980576)

And theyre both good choices for a range of musculoskeletal and rheumatological conditions, including arthritis, ligament injuries, tendonitis, scleroderma, and lupus