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While many individuals with gallstones remain asymptomatic, over 20% experience symptoms, which vary depending on the location of the stones (2, 3)

It should be understood that the following drawings only show some embodiments of the present invention, and thus It should be regarded as a limitation on the scope, and those skilled in the art can also obtain other related drawings based on these drawings without creative work

However, this study was prematurely terminated owing to a change in the drug sponsor (NCT01920477)

These interventions also partially restored gut barrier integrity, reduced renal IgG deposition, and significantly improved kidney function [86]