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130 In a trial in 42 patients with biopsy-diagnosed NASH, treatment with 5 mg melatonin twice daily for 12 weeks resulted in reductions in liver enzyme levels that were maintained during 12 more weeks of treatment but were mostly lost 12 weeks after stopping melatonin therapy

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Watermelon-extract supplementation (Cit: 2.7 g/Arg: 1.3 g) was done for 6 weeks in middle-aged men and women with pre-hypertension, which led to a significant decrease in aortic SBP compared to the placebo controls, as well as a decrease in AIx and pulse wave velocity (PWV) [86]

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PRMT1 upregulated by epithelial proinflammatory cytokines participates in COX2 expression in fibroblasts and chronic antigen-induced pulmonary inflammation

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