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2009;60(Suppl 7):191-196

Peptide therapy addresses numerous conditions including immunosuppression, Hashimotos thyroiditis, Lyme disease, fibromyalgia, Chronic fatigue syndrome, Irritable bowel syndrome, sexual dysfunction, anxiety, and brain fog

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It is an analogue of the ACTH(4-10) fragment of adrenocorticotropic hormone, specifically derived from the ACTH(4-7) core sequence (Met-Glu-His-Phe) the minimal active fragment responsible for the cognitive and neuroprotective activity of ACTH with a C-terminal Pro-Gly-Pro (PGP) tripeptide extension appended to enhance metabolic stability and, as subsequent research has revealed, to contribute independent pharmacological activity of its own

(2003) Peptide regulation of aging [PMID: 12374906, Anisimov VN et al

Media replacement schedules vary based on system design and operational parameters but are typically required every 25 years for most BAC systems