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However, when we studied reporter expression in adult Rosa26-reporter mice using different Cre ERT2 expressing mouse lines, we could not detect changes in age-dependent recombination efficiency or specificity

Per AMA CPT guidelines and AAP coding guidance for pediatric vaccines, the 90471 CPT code has no strict age limit

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These effects are associated with increased intracellular Ca 2+ and transcriptional regulation of genes involved in glucose and amino acid metabolism (31)