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EMBO J (2017) 36(3):2529

The results illustrate the potential of a mechanism-guided therapeutic strategy by targeting a metabolic vulnerability in the ferroptosis of CSCs to improve the efficacy of lung cancer immunotherapy

707,715 Through the combination of these elementary motifs, more complex logic can be achieved such as different types of feed forward loops, 329,715719 negative autoregulation 720 and oscillators

Silencing p53 significantly alleviated PMB-induced iron accumulation and lipid peroxidation, increased the expression of TFR1 and ALOX12, and decreased the expression of GPX4 and SLC7A11 [178]