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doi:10.1016/j.jaip.2023.03.007 12Waldron JL, Rose M, Vogrin S, et al

The underlying clinical question has not changed

Of all types of fat-soluble vitamins, migraine sufferers received lower amounts of vitamins A and K per day (123)

Studies (42, 43) have shown that apigenin has a pro-apoptotic effect in human RA-FLS, and it can induce RA-FLS apoptosis by mediating ROS and oxidative stress activator ERK1/2, and mediate apoptotic cell death by activating the apoptotic effector caspase-3/7

l-Cys is the amino acid establishing disulfide bridges, a type of covalent bond that plays a fundamental role in the folding and stabilization of the tertiary structure of the proteins, thereby supporting their biological activities [2,3]