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Faria CC, Casco R, Custdia C, Paisana E, Carvalho T, Pereira P, et al

On the other hand, many lactobacilli are not capable of producing folate de novo because some genes coding for enzymes involved in folate biosynthesis are lacking in their genome

Reconciling the Contradiction: What the In-Vivo E-Peptide Studies Add The apparent standoff positive early cell-culture reports on one side, a rigorous failed replication on the other is not the whole story, and a fair reading requires bringing in a separate body of in-vivo work that studied the E-peptides differently