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The process from IND to drug approval is not guaranteed...it takes a successful study showing that the drug does in fact work and is safe for the proposed indication

N-acetylcysteine for pediatric obsessive-compulsive disorder: A small pilot study

Of the total baseline population, 68% completed the follow-up questionnaires

Similar to previous findings, we demonstrated that chronic intake of a high-AGE diet shifted the colonic microbiota of a mouse model toward a more detrimental profile, as characterized by the richness of pathogenic bacterial species and depletion of probiotic and SCFAs-producing genera

doi: 10.1186/s13044-016-0031-0 121 ZimmermannMB

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