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Belzung, C

Sorg, O., Didierjean, L

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Carbon from orally administered acetone has been detected in cholesterol, ammo acids, fatty acids and glycogen in rat tissues, urea in urine and unchanged acetone and CO 2 in exhaled breath

Thus and simple bromelain delivery may require high doses of the active principle also due to the characteristics of the extracellular matrix (ECM) which constitutes a barrier that slows down or prevents the spread of drugs in the parenchyma of the tumor