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On a large scale, higher GSH elution productivity, viral genomes, and total particles were observed in 34C batches along with 510-fold higher % empty capsids (Figure 6)

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4.2.1 Stability in Aqueous Solutions In aqueous solution at 25C, SAG exhibits significantly greater stability than unmodified GSH, with substantially lower oxidation rates under identical conditions

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By assuming that the intestine is a straight tube of circular cross-section and that the HagenPoiseuille law is applicable 39,44 , P is given by: where Re is the Reynolds number, L m is the particle migration distance by DMP-induced retrograde or anterograde flow, R is the inner diameter of the intestinal lumen, U is the velocity of retrograde or anterograde flow during the DMP, is the density of the gut contents, and is the viscosity of the gut contents