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Research Use Only Not for human consumption or medical applications

10.1136/bmj.2.5806.131 [DOI] [PMC free article] [PubMed] [Google Scholar] 32

1 Introduction The pathogenesis of autoimmune type 1 diabetes mellitus (T1D) involves infiltration of the pancreatic islet cells by T-lymphocytes, macrophages, and other immune cells with consequent loss of insulin producing -cells ( Outside of the CNS, GABA is highly concentrated in the pancreatic islet wherein it has autocrine and paracrine actions to regulate -cell insulin secretion and inhibit -cell glucagon release

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