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Shahin Homaeigohar, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Elevated intracellular calcium levels drive massive, unchecked ROS production that overwhelms the damaged clearance enzymes

Furthermore, all GSTP-S42A, GSTP-S42D, GSTP-Y198F, and GSTP-Y198D acted the same in suppressing LPS-induced HMGB1 cytoplasmic translocation and release in RAW264.7 cells (Figures 5F,G)

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Furthermore, neurotrophic and antioxidant substances in plants have anti-aging effects on the nervous system and promote the functional integrity of nerve cells