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Regular monitoring, lab testing, and periodic reassessment are essential to reduce potential harm and identify early warning signs

The SCD erythrocytes are then subject to intracellular HbS polymerisation (Pawliuk et al., 2001

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First, KEAP1 has been shown to have complex interactions with various other proteins besides NRF2 (Hushpulian et al., 2021) and concerns about potential side effects arise from the diverse array of cellular processes covered by KEAP1 interactor proteins, involving DNA replication, cytoskeletal dynamics, transcription, and apoptosis

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