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Nakajima T, Wang R-S, Murayama N, & Sato A (1990) Three forms of trichloro-ethylene-metabolizing enzymes in rat liver induced by ethanol, phenobarbital, and 3-methylcholanthrene

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268 COX-2 overexpression and PGE2 production in white adipose tissue could trigger the brownification of preadipocytes, thereby facilitating systemic energy expenditure against diet-induced obesity

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Furthermore, targeting what impairs glutamine to promote its anti-tumor effects can ameliorate therapies, for example, enhancing the expression of glutamine transporters in CD8 + T cells to improve glutamine consumption by these cells in comparison to tumor cells, fostering antitumor immunity