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First, basic insights into OA and ferroptosis confirm that OA progression involves cartilage degeneration, subchondral bone remodeling, and synovial inflammation, in addition to oxidative stress and various cell death modalities

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Grant: Evan Robert Sestak, junior, Deans List, College of Education and Human Sciences, social science

Co-culturing AMSCs with APAP-overdosed AML12 cells increased the expression of OXPHOS subunits and mitochondrial biogenesis-related proteins, whereas SR-18292 inhibited these effects, indicating that PGC-1 was involved in AMSCs-induced mitochondrial biogenesis (Fig

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