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In addition, there is a hybrid receptor with components of the IR (one and one -chain) and the IGF-1R (one and one -chain), to which both insulin and IGF-1 can bind to, but with less affinity than that of their putative receptors [98100]

Juul A, Holm K, Kastrup KW, Pedersen SA, Michaelsen KF, Scheike T, Rasmussen S, Mller J, Skakkebaek NE