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It also appears to influence neurotransmitter regulation, possibly through gutbrain axis pathways, making it a topic of growing interest in neuroregenerative research

Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans

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So, the filopodiumspine transition is unlikely to be a predestined process, but instead one that is reversible and regulated by factors such as synaptic activity