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Those most at risk of a Vitamin B12 deficiency include elderly people, those who follow a vegetarian or vegan diet, people who have had intestinal surgery and people with diseases of the gut, such as Crohn's Disease or Celiac Disease

This same transport route is confirmed by the cumulative AUC-time profiles in CSF and plasma, demonstrating a 30 min delay between plasma absorption and CSF uptake of hydroxocobalamin in rats and in a comparative human study

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Global deletion of monoacylglycerol lipase in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Your doctor may include B12 infections as part of the treatment for conditions that are associated with poor nutrition, malabsorption of vitamin B12 from the intestines or deficiency of this vitamin due to obesity, vegetarian diets, or macrobiotic diets