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To further investigate the functional role of EV uptake in SFR, HCC cells were pre-incubated with EVs derived from HG or LG conditions (HG-EVs, LG-EVs) or with EV-depleted conditioned medium (CM-dEV) (Fig

Metformin treatment also inhibited the phosphorylation of p70-S6 kinase, a typical mTOR substrate, as well as the phosphorylation of STAT3 in HCC cells

Torsin A and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations

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Accordingly, we also observed a negative correlation between VIP and FT4 serum levels in GD patients, whereas no significant relationships were found with other clinical parameters, including TSH, TgAb, TPOAb, and TRAb