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161 In gut microbiota analysis of early-stage liver fibrosis (F0F2), 50% of disease-associated taxa are Enterobacteriaceae, Pseudomonadaceae, Flavobacteriaceae, and Burkholderiaceae, among which Flavobacteriaceae and Xanthomonadaceae can distinguish F0 from F1 stages

Oxidative modifications may alter the properties of affected molecules and impair normal cellular processes

robust human clinical trial evidence remains limited

With aging, the decline in these oscillations compromises core clock function, disrupts mitochondrial homeostasis, and weakens stress responses

Deletion of the p66Shc Longevity Gene Reduces Systemic and Tissue Oxidative Stress, Vascular Cell Apoptosis, and Early Atherogenesis in Mice Fed a High-Fat Diet

Part A: Mol