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Furthermore, serine deprivation induces p53-dependent metabolic reprogramming in cancer cells, including enhanced serine and glutathione synthesis

Chen F, Haigh S, Barman S, Fulton DJ (2012) From form to function: the role of Nox4 in the cardiovascular system

Three rats were used for 2,3,5-triphenyltetrazolium chloride (TTC) staining, three rats were used for histopathological test, four rats were utilized for brain water content, four rats were utilized for brain metabolomics and 16S rRNA sequencing analysis, six rats were chosen to undergo enzyme-linked immunosorbent assay (ELISA) and gut metabolomics analysis in each group

In mitochondria, enzymes involved in the sulfide oxidation pathway, including sulfide:quinone oxidoreductase (SQOR), persulfide dioxygenase (ETHE1) and thiosulfate sulfurtransferase (TST), also contribute to maintaining and regulating intracellular persulfide levels

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En situation de stress oxydatif exposition toxique, inflammation, effort intense ce ratio chute, traduisant un puisement des capacits antioxydantes de la cellule et une accumulation d'ERO qui endommagent les structures cellulaires