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3.4 Therapeutic strategies targeting drug-tolerant persister cells The growing recognition of DTP cells as key intermediates in the resistance continuum has prompted the development of therapeutic strategies to eliminate these resilient populations before the emergence of stable genetic resistance

Combined sample size is roughly 30 patients

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Panobinostat: first global approval

Acknowledgements The authors thank Ann-Cathrine Berg and Eva Hammarstrand for their assistance in clinical data collection and Lisbeth Larsson for her assistance in analyzing the IGF-I and IGFBP-3 samples