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By integrating these findings, this review offers new insights into the role of ferroptosis in joint degeneration and highlights its potential as a therapeutic target in osteoarthritis

115 Targeting DUBs DUBs represent another important target class

These findings suggest that oxidation of hAAT by H 2 O 2 significantly impairs its antiproteolytic activity

J Med Genet 39:400402 Chan DK, Lam MK, Wong R, Hung WT, Wilcken DE (2003) Strong association between N-acetyltransferase 2 genotype and PD in Hong Kong Chinese

Research teams have observed this peptide to bind to the ghrelin or growth hormone secretagogue 1a receptors (GHS-R1a), which are present in the hypothalamus and the pituitary gland