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Closing Statements Every human has the right to enjoy the highest attainable physical and mental health standards

doi: 10.1111/1346-8138.14933 61 Olejniczak-StaruchICiyskaMSobolewska-SztychnyDNarbuttJSkibiskaMLesiakA

A meta-analysis of 28 studies with 74,660 patients who had bioprosthetic valves and atrial fibrillation showed that DOACs were more effective in reducing the risks of bleeding, strokes, systemic embolism, and intracranial bleeding when compared to warfarin

Add in the lack of regulation, potential purity issues, and unknown long-term safety profile, and you have a compound that demands informed decision-making