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Rescue of isolated GH deficiency type II (IGHD II) via pharmacologic modulation of GH-1 splicing

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Cells have developed a sophisticated antioxidant system to protect against these oxidative insults, consisting of enzymes that either convert superoxide radicals into hydrogen peroxide (H 2 O 2 , SOD1, and catalases) or H 2 O 2 into water and oxygen [peroxiredoxin (Prx) and glutathione peroxidase (GPx)

10.3390/proteomes9010006 57 GermainA.RuppertD.LevineS

Reduces autoimmune diseases : The persistent oxidative stress often results in chronic autoimmune diseases such as rheumatoid arthritis

However, only a limited number of studies have been performed to evaluate the toxicity of NSAIDs in the nervous system 15