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2.1 Physical and chemical synthesis Physical methods, such as evaporation-condensation, spark discharge, and pyrolysis, offer rapid synthesis without hazardous chemicals but suffer from high energy consumption, low yield, and inconsistent particle distribution (Kruis et al., 2000

erinaceus subentity and evaluated their hypoglycemic effects, revealing that these polysaccharides effectively reduced body weight and fasting blood glucose levels, improved glucose tolerance, mitigated hepatic lesions in streptozotocin-induced diabetic rats, and positively influenced glycogen synthesis via activation of the phosphatidylinositol 3-kinase/protein kinase B signaling pathway

Non-thermal methods such as ultrasound and cold plasma have had limited use in recent times

Ferroptotic stress promotes macrophages against intracellular bacteria