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OSCs promote CRC cell proliferation by accumulating calcitriol and activating CYP24A1-mediated MAPK signaling (He et al., 2021)

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One form of vitamin E, gamma-tocopherol, was found to increase blood flow by promoting the dilation of blood vessels, potentially reducing blood pressure and the risk of heart disease ( Gamma-tocopherol supplements may also have a blood-thinning effect as well as a reduction effect on LDL (bad) cholesterol levels ( In contrast, other studies suggest that high dose vitamin E supplements may be harmful, even when they dont cause any obvious symptoms of toxicity